Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Related Products (4520)
Related Products (4520)
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α-Truxillic acid
0 Imagesα-Truxillic acid is form by the dimerization of two molecules of α-trans-cinnamic acid, with anti-inflammatory activities. α-Truxillic acid has no analgesic activity, but its derivatives bound to camphor fragments exhibit significant activity in the peripheral analgesic model (writhing test).
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2,5-Difluorophenylboronic acid
0 Images2,5-Difluorophenylboronic acid is a phenylboronic acid substituted with 2,5-difluorine groups. 2,5-Difluorophenylboronic acid serves as an organic synthesis intermediate belonging to the fluorinated phenylboronic acid class.
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FR179642
0 ImagesFR179642 is a key intermediate in the synthesis of the echinocandin antifungal Micafungin. FR179642 is the cyclic peptide nucleus of the echinocandin-like antifungal lipopeptide FR901379.
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Diethyl benzylmalonate
0 ImagesDiethyl benzylmalonate is a drug intermediate that can be used for the synthesis of central inhibitory agents.
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Poly(D,L-lactide-co-glycolide)
0 ImagesCat. No.: HY-W723152CAS No.: 26780-50-7Poly(D,L-lactide-co-glycolide) is a biodegradable polymer copolymer. Poly(D,L-lactide-co-glycolide) undergoes degradation through ester bond hydrolysis into lactic acid and glycolic acid. These two products can be naturally eliminated through metabolism in the body (such as the tricarboxylic acid cycle), without the risk of long-term accumulation. Poly(D,L-lactide-co-glycolide) can be used in medical sutures, implants, and drug delivery systems.
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2-Cyanoethylhydrazine
0 ImagesCat. No.: HY-W001874CAS No.: 353-07-1Synonyms: 3-Hydrazinylpropanenitrile2-Cyanoethylhydrazine (3-Hydrazinylpropanenitrile) is a drug synthesis intermediate that can be used to synthesize an antagonist of opioid receptor-like 1 (ORL1).
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4-Methylbiphenyl
0 ImagesSynonyms: 4-Phenyltoluene4-Methylbiphenyl (4-Phenyltoluene) is an organic compound. 4-Methylbiphenyl has excellent chemical stability and antioxidant properties, and is widely used in industry. 4-Methylbiphenyl can serve as a solvent, coating additive, plastic additive and dye intermediate.
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Fmoc-D-allo-Thr-OH
0 ImagesCat. No.: HY-P4613CAS No.: 130674-54-3Fmoc-D-allo-Thr-OH is a derivative of D-allothreonine (HY-W001959), which is commonly used as a building block in solid-phase peptide synthesis (SPPS).
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3,4-Difluoronitrobenzene
0 Images3,4-Difluoronitrobenzene is a drug intermediate that can be used for the synthesis of oxazolidone antibiotics.
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N2-Isobutyryl-2'-O-methylguanosine
0 ImagesN2-Isobutyryl-2'-O-methylguanosine is a nucleic acid synthesis intermediate (e.g., used in antisense oligonucleotides, mRNA modification), for example, it is a key monomer for the synthesis of 2'-O-methyl oligoribonucleotides. N2-Isobutyryl-2'-O-methylguanosine enables the final product to form stable double strands with complementary RNA and is not easily degraded by nucleases. N2-Isobutyryl-2'-O-methylguanosine is mainly used in molecular biology research, and can be used to prepare RNA hybridization probes or participate in related biochemical research such as pre-mRNA splicing mechanisms.
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DMNB
0 ImagesSynonyms: 6-NitroveratraldehydeDMNB (6-Nitroveratraldehyde) is a photolabile proton donor that releases acidic substances when excited at a wavelength of 405 nM. DMNB can be used for the synthesis of no-carrier-added 6-[18F]fluoro-L-DOPA (6-FDOPA). DMNB is also applicable to the preparation of o-nitroaryl-bis (5-methylfur-2-yl) methanes and the synthesis of alpha-asarone (HY-N0700). DMNB is an enzyme involved in the non-homologous end joining (NHEJ) pathway responsible for DNA double-strand break (DSB) repair. DMNB can be used in PET studies of the dopaminergic system.
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Vanillin acetate
0 ImagesVanillin acetate is a phenol ester that can be synthesized from vanillin by treatment with acetic anhydride.
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Deiodoamiodarone
0 ImagesCat. No.: HY-114928CAS No.: 23551-25-9Synonyms: L 3937; Dideiodo AmiodaroneDeiodoamiodarone (L 3937; Dideiodo Amiodarone) is an intermediate of amiodarone. Amiodarone is a potent calmodulin antagonist.
